Introduction: Numerous studies have indicated the superiority of enteral nutrition compared to parenteral nutrition. The frequency of enteral nutrition-related gastrointestinal complications in critically ill patients is high. Enteral nutrition (gavage) has complications such as diarrhea, nausea, vomiting and gavage intolerance (the residual volume of that which is aspirated from stomach is greater than 50% of the volume that is infused), which may cause fluid and electrolyte imbalance. The goal of this study was to compare the above complications between bolus, intermittent and continuous methods of gavage in surgical intensive care unit (SICU) patients.Materials and methods: After approval of the proposal by the Ethics Committee and obtaining the patients' informed consent, this clinical trial was conducted on 63 SICU patients. Patients were randomly divided into three groups. The methods of gavage used in the three groups were bolus, intermittent and continuous. Data collection was conducted using a checklist on the gavage method and complication data. Statistical analysis was performed with ANOVA and Pearson correlation coefficient was determined.Results: The study showed that the incidence of diarrhea, nausea, and vomiting was not significantly different between the three groups. This study shows that the incidence of diarrhea, nausea and vomiting was not significant between the three groups. Mean+SD durations of gavage tolerance in bolus, intermittent and continuous groups were 13.71+2.19, 13.95+1.35, and 14.85+0.47, respectively. The tolerance of gavage was significantly higher in the continuous groups compared to the bolus group (P<0.05).Conclusions: This study showed that the continuous method of gavage in SICU patients is better tolerated than the bolus method.